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For those of you with warlock alts or just a weird fetish for numbers, here comes some info on Warlocks for the 4.0.1 patch.
All of it shamelessly stolen from MMO-Champion. :)

Please use this link for numbers from this point out
http://elitistjerks.com/f80/t48311-s...4_0_1_numbers/

I'm summarizing here for those who have a hard time reading simcraft extracts.

Definitions:
Affliction = Shadow Bolt spam
Affliction_Drain = Shadow bolt on Nightfall proc, Drain Life spam
Demonology = Normal rotation
Demonology_SP = Searing Pain replaces Shadow Bolt (You still Soul Fire during Decimation and Incinerate during Molten Core)
Destruction_FullSP = Full Searing pain spam
Destruction_NoSP = No searing pain spam*

*You should be using searing pain a lot more than never, but how much is tank dependent.

Gear:
Regear to 17% hit cap (446 hit rating) or as close as you can then...

Gemming:
Regem to hit cap first using full Hit gems in your blue sockets. After this has been reached, Int > Int/Haste (you will have no more hit sockets left imo).
Demonology will gem full Haste and Haste/Int.

Reforging:
Assuming you are hit capped, all specs should reforge spirit and crit to Haste, and if the gear slot has Haste already choose Mastery instead. The exceptions to this rule are Affliction_Drain and Destruction_FullSP which are very difficult specs to play and should not be geared around. However, if you are god and your PC is directly plugged into your realm server, or perhaps you're just insane, these two specs reforge to Mastery across the board.


Scale Factors:
Warlock_401_Affliction Int=4.1835 SP=3.0770 Hit=5.0114 Crit=2.0733 Haste=3.2885 Mastery=2.6345
Warlock_401_Affliction_Drain Int=4.0171 SP=2.9444 Hit=3.5389 Crit=1.9621 Haste=3.1879 Mastery=3.6678
Warlock_401_Demonology Int=3.2822 SP=2.3497 Hit=5.3527 Crit=1.8953 Haste=3.9939 Mastery=2.5535
Warlock_401_Demonology_SP Int=3.3290 SP=2.3998 Hit=4.5287 Crit=1.9552 Haste=2.8467 Mastery=2.1638
Warlock_401_Destruction Int=3.5955 SP=2.6964 Hit=5.9315 Crit=1.9349 Haste=2.7184 Mastery=2.8300
Warlock_401_Destruction_FullSP Int=3.7377 SP=2.8151 Hit=5.9967 Crit=2.0065 Haste=2.3669 Mastery=2.9829
Warlock_401_Destruction_NoSP Int=3.3966 SP=2.5421 Hit=5.7613 Crit=1.8817 Haste=2.9728 Mastery=2.5760

Affliction:
Succubus Pet
Glyphs: Lash of Pain, Life Tap, Unstable Affliction, Shadowbolt
Priorities: (does not reflect initial cast sequence)
Haunt, Doom, Corruption, Soulburn UA, UA, Drain Soul Execute, Doomguard, Shadow Bolt, Life Tap

Affliction_Drain:
Succubus Pet
Glyphs:
Glyphs: Lash of Pain, Life Tap, Unstable Affliction, Shadowbolt
Priorities: (does not reflect initial cast sequence)
Haunt, Doom, Corruption, UA, Drain Soul Execute, Doomguard, Shadow Bolt (Nightfall), Soulburn Drain Life, Drain Life, Life Tap

Demonology:
Felguard Pet
Glyphs:
Life Tap, Shadow Bolt, Immolate, Incinirate, Metamorphosis
Priorities:
Meta, Soulburn Soul Fire, Immolate, Doom, Hand of Guldan, Immolation Aura, Corruption, Decimation Soul Fire, Molten Core Incinerate, Shadow Bolt, Life Tap

Demonology_SP:
Felguard Pet
Glyphs:
Life tap, Shadowbolt, Immolate, Incinerate, Metamorphosis (Still use shadow bolt because theres nothing else...)
Priorities:
Meta, Soulburn Soul Fire, Immolate, Doom, Hand of Guldan, Immolation Aura, Corruption, Decimation Soul Fire, Molten Core Incinerate, Searing Pain, Life Tap

Destruction_FullSP:
Imp Pet
Glyphs:
Conflagrate, Immolate, Imp, Life Tap
Priorities: (Does not reflect initial cast sequence)
Doom, Immolate, Conflagrate, Doomguard, Soulburn Soul Fire, Soul Fire for haste buff, Chaos Bolt, Corruption, Soulfire (Imp Proc), Searing Pain, Life Tap

Destruction_NoSP:
Imp Pet
Glyphs:
Conflagrate, Immolate, Imp, Life Tap
Priorities: (Does not reflect initial cast sequence)
Doom, Immolate, Conflagrate, Doomguard, Soulburn Soul Fire, Soul Fire for haste buff, Chaos Bolt, Corruption, Soulfire (Imp Proc), Incinerate, Life Tap

Talents:
Affliction: http://cata.wowhead.com/talent#IrhrousGcdZG:sbRbo
Affliction_Drain: http://cata.wowhead.com/talent#IrhrousGcdZf:sbRbo
Demonology: http://cata.wowhead.com/talent#IZcdrfourRdoG:mVabo
Demonology_SP: http://cata.wowhead.com/talent#IZcdrfourRdocb:mVabo
Destruction_FullSP: http://cata.wowhead.com/talent#I0bZcZIrrcMbskdo:zoVb
Destruction_NoSP: http://cata.wowhead.com/talent#I0bZcZIrrcMbskdo:zoVb

Notable change to affliction is that you now use Succubus instead of the Fel-puppy. Higher DPS up until around lvl 83 when you are able to take 3 points in Dark Arts. From what I've heard, Felhunter will then outperform Succubus due to the boost to Shadow Bite.

New Hit cap is 446. This due to removed or remade talents for Shadowpriests/Boomkins I figure?

Seems Destruction will actually start using Searing pain as part of the rotation now. Used to be a big NO-NO due to the insane aggro-generation of that spell (what Warlock used to spam when tanking in some encounters). Need to keep a close watch on threat-meters when using that, and Tanks beware!
My guess is that Blizz will change this by either nerfing Searing pain or buffing Incinerate though. Think they still intend for it to be a PvP/occasional tanking tool.

Corruption also seems to be in the Destro rotation (EJ recommends 2 points in Improved Corruption as you can see in the talent trees) as well as Soul Fire for the 15% haste buff.

Also, both Infernal and Doomguard are now "extra" pets that can be summoned with a CD.

Edit: Good post over @ Elitist Jerks regarding Warlock pre-cata raiding http://elitistjerks.com/f80/t106168-4_0_pre_cataclysm_raiding/